Electron microscopy sciences propylene oxide, em grade, 75569, mfcd00005126, 450ml manufacturer. Carcinogenic effects of exposure to propylene oxide cdc. Suitable catalysts include sodium hydroxide, potassium hydroxide, tertiary amines, potassium carbonate, sodium acetate, boron triflouride, and acid clays. Propylene oxide description propylene oxide is a clear, volatile and inflammable liquid. Repeated exposure can result in significant skin absorption. Process propylene glycol diacetate is produced by the reaction of propylene oxide with acetic acid using a catalyst. Occupational exposure limits for chemical substances, occupational health and safety regulation 29697, as amended 07 2007 propylene oxide twa 2 ppm canada.
Pdf direct oxidation of propylene to propylene oxide. Take the time to validate and double check the source of the data. Propylene oxide is also used to manufacture functional fluids by reaction of propylene oxide or mixtures of propylene oxide and ethylene oxide with glycols, glycerin, alcohols, and phenols. The ld 50 of propylene imine on oral ingestion of a single dose by rats is 19 mgkg.
It became an important basic raw material that can be used in a wide range of industrial and commercial products. Propylene oxide may react vigorously with oxidizing materials, anhydrous metal halides, acids, bases, claybased adsorbent materials, and peroxides. Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. Propylene oxide pdf, 41kb propylene oxide urethane grade pdf, 38kb propylene oxide handling pdf, 38kb huntsman internationals state of the art propylene oxide po production facility utilizes proprietary technology to produce po and coproduct methyl tertiary butyl ether mtbe by one of the lowest cost routes available today.
About 60% of the propylene oxide produced annually by dow is used to. Media in category propylene oxide the following 23 files are in this category, out of 23 total. This structure is also available as a 2d mol file or as a computed 3d sd file the 3d structure may be viewed using java or javascript. First aid eye contact f fimmediately flush with large amounts of water for at least 30. The types of functional fluids produced include heat transfer fluids, hydraulic fluids, and lubricants. Control of exposure to biological or chemical agents, as amended 11 2010 propylene oxide twa 20 ppm 48 mgm3 canada.
Pdf direct oxidation of propylene to propylene oxide with. Studyhazard statement category 1 category 2 category 3 category 4 category 5. Department of transportation hazard labels, and a general description of the chemical. Product safety assessment ucar propylene glycol aircraft.
The source is also providing more information like the publication year, authors and more. Propylene oxide splashed in the eye can cause severe burning, tearing, redness, swelling and corneal burns, propylene oxide vapors also can cause. Electron microscopy sciences 20401 molecular formula c3h6o, molecular weight 58. Acute shortterm exposure of humans and animals to propylene oxide has caused eye and respiratory tract irritation. Volatilization of propylene oxide from the aquatic environment may be an. Handling and storage advice on general occupational hygiene conditions for safe storage, including any incompatibilities eating, drinking and. Decomposition of propylene carbonate on the graphite electrode in lithium batteries results in the formation of a lithium intercalated compound. Propylene oxide reacts with the hydroxyl group of alcohols and phenols to produce monoethers of propylene glycol.
Propylene glycols consume another 20% of the total, and propylene glycol ethers consume about 5%. Propylene oxide technical data sheet, the dow chemical. Workplace exposure exposure can occur either in a facility that manufactures propylene oxide or in the various industrial or manufacturing facilities that use propylene oxide. This organic, highly reactive compound is a major commodity chemical, as well as starting material for several products, from polymers and solvents to industrial. Firefighting measures promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. It is used in the production of polypropylene, propylene oxide, acrylonitrile, cumene, acrylic acid and other products 1, 2. Superfund amendments and reauthorization act of 1986 sara hazard categories not classified not classified sara 302 extremely hazardous substance chemical identity reportable quantity threshold planning quantity ethylene oxide 10 lbs. Identification of the substancemixture and of the companyundertaking date issued 04.
Do not extinguish, unless leak can be stopped safely. This colourless volatile liquid with an odour resembling ether, is produced on a large scale industrially. Po, epoxypropane, methyl oxirane is a synthetic, highlyflammable, volatile, colorless liquid that is soluble in water and miscible with most organic solvents. Based on the uses for this product, the public could be exposed through. Consumers may be exposed through ingestion of propylene oxide residues in foods resulting from its use as an indirect food additive or by contact with. Optically active form of propylene carbonate can be prepared from the reaction between co 2 and racemic epoxides. The information in cameo chemicals comes from a variety of data sources. Superfund amendments and reauthorization act of 1986 sara hazard categories immediate acute health hazards sara 302 extremely hazardous substance chemical identity reportable quantity threshold planning quantity propylene oxide 100 lbs. No action shall be taken involving any personal risk or without suitable training. Propylene oxide mixed with ammonium hydroxide, chlorosulfonic acid. Ministry of labor regulation respecting the quality of the work environment, as amended 09 2017 appropriate engineering controls. Propylene oxide technical bulletin page 2 of 3 chemical control laws australia, aics listed canada, dsl listed europe, einecs listed japan, meti listed united states, tsca listed physical properties chlorides inorganic as cl, ppm 0. Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
Propylene oxide is used primarily as a chemical intermediate in the production of polyethers and propylene glycol. The optimum position of the po was shown to be a single discrete block of po located in approximately the middle of the ethoxylate chain. Physical and surface active properties of ethoxylates are altered by the inclusion of propylene oxide po groups. Consumers may be exposed through ingestion of propylene oxide residues in foods resulting from its use as an indirect food additive or by contact with consumer products containing propylene oxide. Chemeo is only indexing the data, follow the source links to retrieve the latest data. Sales specification characteristics unit specification appearance clear viscous liquid density at 25 0c gcc 1. Propylene oxide po was first prepared in 1861 by oser, and first polymerized by levene and walti in 1927 1.
This material does not contain any class 1 ozone depletors. Its major application is its use for the production of polyether polyols for use in making polyurethane plastics. Nonionic surfactants containing propylene oxide springerlink. Msds30390072005e 11 toxicological information oral toxicity. This structure is also available as a 2d mol file or as a computed 3d sd. It is among the top 50 chemicals produced by volume in the world. Box 4980 the woodlands, tx 77387 telephone numbers transportationemergency chemtrec. Propylene oxide is a stable material that will not decompose under normal conditions of temperature and pressure. Propylene oxide current prices petrochemicals prices. Methyloxirane, 12 epoxypropane, methyl ethylene oxide, propylene epoxide.
Control of exposure to biological or chemical agents, as amended 11 2010. The direct oxidation of propylene to propylene oxide po using molecular oxygen has many advantages over existing chlorohydrin and hydroperoxide process, which produce side products and require. It is a chiral epoxide, although it is commonly used as a racemic mixture. Propylene oxide in liquid or solid solution form may be absorbed through the skin and produce toxic effects. Propylene oxide is used in the production of industrial and consumer products. Aspiration of material into the lungs may cause chemical pneumonitis, which may be. Sigma aldrich offers a number of propylene oxide products.
Global demand for propylene increased from 65 million tonyear in. Identification of the substancemixture and of the companyundertaking 1. Product data and technical information corporate statement. This relatively low ld 50 indicates that propylene imine is a poisonous material and extreme care should be used to avoid ingestion.
Lyondellbasell is the worlds leading producer of propylene oxide po, a commodity chemical used in the manufacturing of thousands of everyday products, ranging from antifreeze to cosmetics. The location of po within the ethoxylate eo chain can be as important a factor as the relative amounts of po and eo. The chemical identifier fields include common identification numbers, the nfpa diamond u. Polyether polyols consume the largest share of propylene oxide using between 6070% of the total global volume. P280 wear protective gloves protective clothing eye protection face protection. It evaporates quickly and is completely soluble mixes easily in water. Lewis, environment canada, ottawa, canada published under the joint sponsorship of the united nations environment programme, the. Peak air concentrations ranged from 10 to 3,800 ppm, with the highest exposures occurring during maintenance operations flores 1983. Propylene oxide and propylene oxide monitoring interscan. Ethylene oxide please note that the layout and pagination of this pdf file are not identical to those of the printed cicad first draft prepared by r. Propylene oxide technical bulletin huntsman corporation. Details of the supplier of the safety data sheet praxair, inc. Poloxamer 182 may contain trace amounts of ethylene oxide, propylene oxide, and. Material safety data sheet validation date product and company identification 1.
Data file distributed in 2 diskettes by office of pollution, prevention, and toxics, environmental protection agency, washington, dc. November 22, 2015 the dow chemical company page 2 of 5 manufacture of product3 capacity western europe is the largest producer and consumer of propylene oxidebased glycol ethers. Dispose of contentscontainer in accordance with localregionalnational international regulations. Read the product manufacturers material safety data. Prevent from entering sewers, basements and workpits, or any place where its accumulation can be dangerous. Propylene oxide is a chemical intermediate used to make a wide range of industrial and consumer products.
Propylene oxide reacts with water to produce propylene glycol 57556, dipropylene glycol, tripropylene. Relevant identified uses of the substance or mixture and uses advised against use of the substancemixture. June 15, 2015 the dow chemical company page 2 of 6 type i deicing fluid 80% type iv antiicing fluid 20% use of ucartm pgbased deicing fluids and antiicing fluids12 manufacture of product. It is also used as a pesticide and a fumigant for the sterilization of packaged foods. Further addition of propylene oxide yields the di, tri, and. Propylene oxide urethane grade pdf, 38kb propylene oxide handling pdf, 38kb huntsman internationals state of the art propylene oxide po production facility utilizes proprietary technology to produce po and coproduct methyl tertiary butyl ether mtbe by one of the lowest cost routes available today. Move containers from fire area if this can be done without risk. Electron microscopy sciences propylene oxide, em grade, 75.
Derivatives of propylene oxide, such as polyether polyols and propylene glycols, are used in foods. Propylene oxide 75569 hazard summary propylene oxide is used in the production of polyethers the primary component of polyurethane foams and propylene glycol. Propylene oxide is an organic compound with the molecular formula ch 3 chch 2 o. Propylene oxide is a synthetic, highlyflammable, volatile, colorless liquid that is soluble in water and miscible with many organic solvents. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. Propylene oxide reacts with water to produce propylene glycol 57556, dipropylene glycol, tripropylene glycol, and higher molecular weight polyglycols. About 60% of the propylene oxide produced annually by dow is used to manufacture polyether polyols, a major component of polyurethane foam. Dermal contact, even with dilute solutions, has caused skin. Back to top product description1,5 propylene glycol diacetate pgda is a colorless liquid with a slight etherlike odor. Msds 30390072005e 11 toxicological information oral toxicity. It is also used as a pesticide and a fumigant for the sterilization of packaged foods and plastic medical instruments. Ucar propylene glycol aircraft deicing and antiicing fluids revised.
Product identifier product name monopropylene glycol mpg chemical name 1,2propylenglykol reach reg no. Handling and storage advice on general occupational hygiene conditions for safe storage, including any incompatibilities eating, drinking and smoking should be prohibited in areas where this material is. An industrial hygiene study conducted at a propylene oxide producing plant in the united states found timeweighted average twa exposures to propylene oxide ranging from 0. Safety data sheet monopropylene glycol mpg section 1. Determine impurities in highpurity propylene oxide with. Ventilation equipment should be explosionresistant if explosive concentrations of material are present.
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